Renal Insufficiency: Blood vessels made in the laboratory

Published by Jackson Ville on

Human blood vessels developed in the lab have been successfully transplanted to human circulatory systems. The blood vessels come from the recipient’s own tissues and could be used to replace arteries damaged by kidney disease.

A team of researchers based in Durham, North Carolina, grew blood vessels using human smooth muscle cells, found in arteries and veins.

The technique

These cells were spread over a scaffold and supplied with nutrients. They produced an extracellular matrix, a 3D network of proteins, including collagen, to make blood vessels. When the vessels formed, fluids were introduced into them to simulate the pressure of the blood being pumped through the body.

The researchers separated the cells from the vessels, removing proteins that could be recognized as foreign by the recipient’s immune system. They then implanted the 42 centimeter long and 6 millimeter diameter vessels in the arms of 60 people with kidney failure.

The results

Samples taken from 13 people over a four-year period showed that the blood vessels developed into multi-layered, self-healing tissues after injury, thus truly becoming the person’s own vessels.

Blood vessel replacements are necessary in many situations, such as when the arteries are damaged by trauma or cardiovascular disease. Coronary artery bypass surgery, for example, involves the transplantation of vessels to restore normal blood flow to the heart.


The advantage of bioengineered vessels over synthetic polymer implants is that they showed no signs of rejection or inflammatory reactions.

It took about two months for a batch of blood vessels to grow in the lab. The team is now stepping up the process, hoping to produce tens of thousands a year.


หาเงินจากยูทูป · December 7, 2020 at 5:43 pm

What’s up, just wanted to mention, I liked this article.
It was inspiring. Keep on posting!

Scandinavian walking app · December 22, 2020 at 11:21 am

Hi to all, how is all, I think every one is getting more from this website, and your views are nice for new

idn poker · January 14, 2021 at 5:08 pm

Hello there! I know this is kinda off topic but I was wondering which blog platform are you using for this website?
I’m getting fed up of WordPress because I’ve had problems with hackers and I’m looking at options for another platform.
I would be awesome if you could point me in the direction of a good platform.

idnpoker · January 15, 2021 at 6:37 am

The other day, while I was at work, my sister stole my
apple ipad and tested to see if it can survive a twenty five foot drop,
just so she can be a youtube sensation. My iPad is now destroyed and she has 83 views.
I know this is completely off topic but I had to share it with someone!

Fence · February 4, 2021 at 4:07 pm

Hi there to every , since I am genuinely keen of reading this weblog’s post to be updated daily.
It consists of good data.

หวยเด็ด · February 6, 2021 at 7:08 pm

When I originally commented I clicked the “Notify me when new comments are added” checkbox and now each time a comment is added I get four e-mails with the same comment.
Is there any way you can remove people from that service?
Many thanks!

Fence · February 7, 2021 at 4:03 am

You should take part in a contest for one of the best websites
on the net. I am going to recommend this blog!

Leave a Reply

Your email address will not be published. Required fields are marked *